Characterising the contribution of Hrd1 complex components to the UPR: Implications for cancer cell survival

<p>The Hrd1 complex is a large multiprotein complex that spans the endoplasmic reticulum (ER) membrane with Hrd1 itself functioning as an E3 ligase in the endoplasmic reticulum associate degradation (ERAD) pathway in which unfolded and misfolded proteins are cleared from the ER in order to mai...

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Bibliographic Details
Main Author: Evans, GT
Other Authors: Christianson, J
Format: Thesis
Language:English
Published: 2023
Subjects: