Identification of human-to-human transmissibility factors in PB2 proteins of influenza A by large-scale mutual information analysis
Background: The identification of mutations that confer unique properties to a pathogen, such as host range, is of fundamental importance in the fight against disease. This paper describes a novel method for identifying amino acid sites that distinguish specific sets of protein sequences, by compara...
Main Authors: | , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2007
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