Functionalised bicyclic tetramates derived from cysteine as antibacterial agents.

Routes to bicyclic tetramates derived from cysteine permitting ready incorporation of functionality at two different points around the periphery of a heterocyclic skeleton are reported. This has enabled the identification of systems active against Gram-positive bacteria, some of which show gyrase an...

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Bibliographic Details
Main Authors: Panduwawala, TD, Iqbal, S, Thompson, AL, Genov, M, Pretsch, A, Pretsch, D, Liu, S, Ebright, RH, Howells, A, Maxwell, A, Moloney, MG
Format: Journal article
Language:English
Published: Royal Society of Chemistry 2019