General synthesis of sugar-derived azepane nitrones: precursors of azepane iminosugars.

A general and efficient method has been developed for the synthesis of sugar-derived azepane nitrones starting from aldohexoses, with an intramolecular condensation of aldehyde and hydroxylamine as the key step. Through this strategy, each aldohexose produced a pair of azepane nitrones, which are pr...

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Bibliographic Details
Main Authors: Zhao, W, Nakagawa, S, Kato, A, Adachi, I, Jia, Y, Hu, X, Fleet, G, Wilson, F, Horne, G, Yoshihara, A, Izumori, K, Yu, C
Format: Journal article
Language:English
Published: 2013