General synthesis of sugar-derived azepane nitrones: precursors of azepane iminosugars.

A general and efficient method has been developed for the synthesis of sugar-derived azepane nitrones starting from aldohexoses, with an intramolecular condensation of aldehyde and hydroxylamine as the key step. Through this strategy, each aldohexose produced a pair of azepane nitrones, which are pr...

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Main Authors: Zhao, W, Nakagawa, S, Kato, A, Adachi, I, Jia, Y, Hu, X, Fleet, G, Wilson, F, Horne, G, Yoshihara, A, Izumori, K, Yu, C
Format: Journal article
Language:English
Published: 2013
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author Zhao, W
Nakagawa, S
Kato, A
Adachi, I
Jia, Y
Hu, X
Fleet, G
Wilson, F
Horne, G
Yoshihara, A
Izumori, K
Yu, C
author_facet Zhao, W
Nakagawa, S
Kato, A
Adachi, I
Jia, Y
Hu, X
Fleet, G
Wilson, F
Horne, G
Yoshihara, A
Izumori, K
Yu, C
author_sort Zhao, W
collection OXFORD
description A general and efficient method has been developed for the synthesis of sugar-derived azepane nitrones starting from aldohexoses, with an intramolecular condensation of aldehyde and hydroxylamine as the key step. Through this strategy, each aldohexose produced a pair of azepane nitrones, which are precursors of various azepane iminosugars.
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spelling oxford-uuid:f1ee9f5d-deb2-44d1-beed-152adb0f7e9b2022-03-27T11:59:50ZGeneral synthesis of sugar-derived azepane nitrones: precursors of azepane iminosugars.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:f1ee9f5d-deb2-44d1-beed-152adb0f7e9bEnglishSymplectic Elements at Oxford2013Zhao, WNakagawa, SKato, AAdachi, IJia, YHu, XFleet, GWilson, FHorne, GYoshihara, AIzumori, KYu, CA general and efficient method has been developed for the synthesis of sugar-derived azepane nitrones starting from aldohexoses, with an intramolecular condensation of aldehyde and hydroxylamine as the key step. Through this strategy, each aldohexose produced a pair of azepane nitrones, which are precursors of various azepane iminosugars.
spellingShingle Zhao, W
Nakagawa, S
Kato, A
Adachi, I
Jia, Y
Hu, X
Fleet, G
Wilson, F
Horne, G
Yoshihara, A
Izumori, K
Yu, C
General synthesis of sugar-derived azepane nitrones: precursors of azepane iminosugars.
title General synthesis of sugar-derived azepane nitrones: precursors of azepane iminosugars.
title_full General synthesis of sugar-derived azepane nitrones: precursors of azepane iminosugars.
title_fullStr General synthesis of sugar-derived azepane nitrones: precursors of azepane iminosugars.
title_full_unstemmed General synthesis of sugar-derived azepane nitrones: precursors of azepane iminosugars.
title_short General synthesis of sugar-derived azepane nitrones: precursors of azepane iminosugars.
title_sort general synthesis of sugar derived azepane nitrones precursors of azepane iminosugars
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