Toll-like receptors differentially induce nucleosome remodelling at the IL-12p40 promoter
Toll‐like receptors (TLRs) mediate recognition of microbial components. Despite activation of a shared set of signal transduction molecules, the biological effects of certain TLR agonists differ considerably. In macrophages and dendritic cells, stimulation by the prototypical stimuli CpG‐DNA (TLR9),...
Main Authors: | , , , , , |
---|---|
Format: | Journal article |
Published: |
EMBO Press
2004
|