Molecular mechanisms involved in T cell receptor triggering.

Despite intensive investigation we still do not understand how the T cell antigen receptor (TCR) tranduces signals across the plasma membrane, a process referred to as TCR triggering. Three basic mechanisms have been proposed, involving aggregation, conformational change, or segregation of the TCR u...

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Bibliographic Details
Main Authors: Choudhuri, K, Van Der Merwe, P
Format: Journal article
Language:English
Published: 2007