Efficient RNA synthesis by in vitro transcription of a triazole-modified DNA template.
A DNA strand containing a triazole phosphodiester mimic is an efficient template for in vitro transcription. This is the first demonstration of transcription through a heavily modified DNA backbone linkage and it suggests that click-ligated DNA could be useful for the direct synthesis of biologicall...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2011
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