Understanding human fetal pancreas development using subpopulation sorting, RNA sequencing and single-cell profiling

To decipher the populations of cells present in the human fetal pancreas and their lineage relationships, we developed strategies to isolate pancreatic progenitors, endocrine progenitors and endocrine cells. Transcriptome analysis of the individual populations revealed a large degree of conservation...

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Bibliographic Details
Main Authors: Ramond, C, Beydag-Tasöz, BS, Azad, A, van de Bunt, M, Petersen, MBK, Beer, NL, Glaser, N, Berthault, C, Gloyn, AL, Hansson, M, McCarthy, M, Honoré, C, Grapin-Botton, A, Scharfmann, R
Format: Journal article
Published: Company of Biologists 2018