Inflammatory bowel disease in C.B-17 scid mice reconstituted with the CD45RBhigh subset of CD4+ T cells.

Chronic inflammation developed spontaneously in the large intestine of C.B-17 scid mice restored with the CD45RBhigh subset of CD4+ T cells obtained from normal BALB/c mice. The inflammation, which extended diffusely from the cecum to the rectum, was localized to the lamina propria of mildly affecte...

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Bibliographic Details
Main Authors: Leach, M, Bean, A, Mauze, S, Coffman, R, Powrie, F
Format: Journal article
Language:English
Published: 1996