Purified lymphocyte function-associated antigen-3 and T11 target structure are active in CD2-mediated T cell stimulation.

In this study we have used cells expressing LFA-3 or T11TS, the human and sheep forms of the ligand of CD2, as well as the purified LFA-3 and T11TS molecules themselves to study their effects on T cell activation via the CD2-mediated "alternative pathway". Sheep red blood cells, which bind...

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Bibliographic Details
Main Authors: Tiefenthaler, G, Hünig, T, Dustin, M, Springer, T, Meuer, S
Format: Journal article
Language:English
Published: 1987