PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes.

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes.

DNA microarrays can be used to identify gene expression changes characteristic of human disease. This is challenging, however, when relevant differences are subtle at the level of individual genes. We introduce an analytical strategy, Gene Set Enrichment Analysis, designed to detect modest but coord...

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Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Mootha, V, Lindgren, C, Eriksson, K, Subramanian, A, Sihag, S, Lehar, J, Puigserver, P, Carlsson, E, Ridderstråle, M, Laurila, E, Houstis, N, Daly, M, Patterson, N, Mesirov, J, Golub, T, Tamayo, P, Spiegelman, B, Lander, E, Hirschhorn, J, Altshuler, D, Groop, L
Μορφή: Journal article
Γλώσσα:English
Έκδοση: 2003

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