Cytotoxic T-cell antagonism in HIV-1

The cytotoxic T-cell (CTL) response to human immunodeficiency virus Type 1 (HIV-1) is vigorous and sustained, but despite this, the virus persists. Natural variation arising within CTL epitopes may affect CTL recognition of infected targets and allow viral escape. Some of these variant epitopes appe...

Full description

Bibliographic Details
Main Authors: Klenerman, P, Phillips, R, McMichael, A
Format: Journal article
Language:English
Published: 1996