Pause sites promote transcriptional termination of mammalian RNA polymerase II.

Polymerase II (Pol II) transcriptional termination depends on two independent genetic elements: poly(A) signals and downstream terminator sequences. The latter may either promote cotranscriptional RNA cleavage or pause elongating Pol II. We demonstrate that the previously characterized MAZ4 pause el...

Полное описание

Библиографические подробности
Главные авторы: Gromak, N, West, S, Proudfoot, N
Формат: Journal article
Язык:English
Опубликовано: 2006