Pause sites promote transcriptional termination of mammalian RNA polymerase II.

Polymerase II (Pol II) transcriptional termination depends on two independent genetic elements: poly(A) signals and downstream terminator sequences. The latter may either promote cotranscriptional RNA cleavage or pause elongating Pol II. We demonstrate that the previously characterized MAZ4 pause el...

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Main Authors: Gromak, N, West, S, Proudfoot, N
格式: Journal article
语言:English
出版: 2006