Use of genome wide expression profiles in analysis of T cell dysfunction in Hepatitis C virus infection

Use of genome wide expression profiles in analysis of T cell dysfunction in Hepatitis C virus infection

<p>During the course of infection with chronic pathogens such as Hepatitis C virus (HCV), Hepatitis B virus (HBV) and HIV, virus-specific CD8<sup>&plus;</sup> T cells differentiate into heterogeneous dysfunctional subpopulations. Advances in multi-parameter flow cytometry h...

Полное описание

Библиографические подробности
Главный автор:	Gupta, P
Другие авторы:	Klenerman, P
Формат:	Диссертация
Язык:	English
Опубликовано:	2014
Предметы:	Gastroenterology Medical sciences Genetics (medical sciences) Infectious diseases Immunology

Схожие документы

Genetic studies in ulcerative colitis
по: Bryant, RV
Опубликовано: (2015)

Implications of HCV genotype 3 specific immunity on cross-reactive vaccine design
по: von Delft, A, и др.
Опубликовано: (2014)

The role of IL-1beta in intestinal inflammation
по: Coccia, M, и др.
Опубликовано: (2011)

The role of the IL23/IL17 pathway in inflammatory bowel disease
по: Geremia, A
Опубликовано: (2011)

Investigation of the signalling and function of NOD2
по: Brain, A
Опубликовано: (2013)

Function, phenotype and development of human CD161+CD8 T cells
по: Walker, LJ
Опубликовано: (2012)

Host and viral factors that determine the clinical outcome of hepatitis C virus genotype 3a infection
по: Humphreys, I, и др.
Опубликовано: (2011)

The function of NOD2 in antigen presenting cells
по: Allan, P
Опубликовано: (2012)

Host genetic factors and vaccine-induced immunity to hepatitis B virus infection
по: Hennig, B, и др.
Опубликовано: (2008)

Forward genetic and cellular studies of immune regulation: the roles of Carma1, Interleukin-10 and Gimap5
по: Barnes, MJ
Опубликовано: (2010)

Characterising immune responses to viral vectored vaccines against influenza and hepatitis C
по: Antrobus, R
Опубликовано: (2014)

Whole-genome sequencing demonstrates that fidaxomicin is superior to vancomycin for preventing reinfection and relapse of infection with Clostridium difficile
по: Eyre, D, и др.
Опубликовано: (2013)

B cell and antibody responses to influenza a virus in human
по: Huang, K
Опубликовано: (2011)

Inflammatory and myeloid-associated gene expression before and one day after infant vaccination with MVA85A correlates with induction of a T cell response.
по: Matsumiya, M, и др.
Опубликовано: (2014)

Novel adenoviral vectored vaccines and the implications of viral diversity in therapeutic strategies against Hepatitis C Virus infection
по: Kelly, C
Опубликовано: (2013)

Characterisation of expression and function of respiratory epithelial CD1d
по: Hajipouran Benam, K
Опубликовано: (2014)

Contribution of monocytes to immunopathology during influenza A virus infection
по: Cole, S, и др.
Опубликовано: (2014)

B cell response to pneumococcal vaccines
по: Trück, J
Опубликовано: (2014)

Functional analysis of cancer-causing FBXW7 mutations
по: Davis, HL
Опубликовано: (2012)

The role of T cell immunity in natural influenza A infection in a UK cohort: flu watch
по: Wang, L
Опубликовано: (2014)

Advances in pediatrics in 2017: current practices and challenges in allergy, endocrinology, gastroenterology, genetics, immunology, infectious diseases, neonatology, nephrology, neurology, pulmonology from the perspective of Italian Journal of Pediatrics
по: Carlo Caffarelli, и др.
Опубликовано: (2018-07-01)

Functional genomics of severe sepsis and septic shock
по: Radhakrishnan, J
Опубликовано: (2013)

Allele specific gene expression in the major histocompatibility complex
по: Plant, K
Опубликовано: (2012)

Investigation of expression quantitative trait loci and regulatory genetic variants in primary human immune cells
по: Makino, S
Опубликовано: (2013)

Connective tissue changes in patients with rectal prolapse
по: Smyth, EAE
Опубликовано: (2012)

The role of the cytoplasmic domain of the macrophage scavenger receptor MARCO in adhesion and uptake
по: Kroos, M
Опубликовано: (2008)

Memory T cell responses in influenza A infection and vaccination in humans
по: Chui, C
Опубликовано: (2012)

Genetics determinants of vaccine responses
по: O'Connor, D
Опубликовано: (2014)

Genome-wide DNaseI hypersensitive sites profiles in laboratory mouse strains by DNase-seq
по: Hosseini, M
Опубликовано: (2013)

Evaluation of a human BCG challenge model to assess antimycobacterial immunity induced by BCG and a candidate TB vaccine, MVA85A, alone and in combination
по: Harris, S, и др.
Опубликовано: (2013)

Functional impact of CD161 on T cells
по: Smith, K
Опубликовано: (2013)

Impact of genetic variation on gene regulatory effects of vitamin D in immunity and inflammation
по: Berlanga-Taylor, A
Опубликовано: (2013)

The functional consequences of autoimmune variants in the tyrosine kinase 2 gene region
по: Shipman, L
Опубликовано: (2014)

Diarrhoeal disease in children under the age of five in Ho Chi Minh City, Vietnam
по: Phan, V, и др.
Опубликовано: (2013)

Homozygosity and risk of childhood death due to invasive bacterial disease
по: Lyons, E, и др.
Опубликовано: (2009)

Epigenetic regulation of the myeloid cell lineage
по: Pliuskys, L
Опубликовано: (2014)

Analysis of b cell responses to blood-stage malaria antigens in humans following immunization with candidate vaccines and controlled human malaria infection
по: Elias, SC
Опубликовано: (2014)

The molecular epidemiology of dengue virus serotype 4 in Bangkok, Thailand
по: Klungthong, C, и др.
Опубликовано: (2004)

Accessing complex genomic variation in Plasmodium falciparum natural infections
по: Wendler, J
Опубликовано: (2015)

Control of expression of human snRNA genes
по: Zaborowska, J, и др.
Опубликовано: (2013)