Cis-acting sequences regulating expression of the human alpha-globin cluster lie within constitutively open chromatin.

Cis-acting sequences regulating expression of the human alpha-globin cluster lie within constitutively open chromatin.

Current models suggest that tissue-specific genes are arranged in discrete, independently controlled segments of chromatin referred to as regulatory domains. Transition from a closed to open chromatin structure may be an important step in the regulation of gene expression. To determine whether the h...

Полное описание

Библиографические подробности
Главные авторы:	Vyas, P, Vickers, M, Simmons, D, Ayyub, H, Craddock, C, Higgs, D
Формат:	Journal article
Язык:	English
Опубликовано:	1992

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