Massive CD8 T cell response to primary HIV infection in the setting of severe clinical presentation.
Acute HIV-1 infection causes a rapid total body depletion of CD4(+) T cells in most individuals and HIV-1-specific CD8(+) T cell expansion in response to viral replication. A numerically high CD8 T cell response may indicate limited T cell repertoire against HIV and rapid progression. We present a d...
Hlavní autoři: | Arnoczy, G, Ferrari, G, Goonetilleke, N, Corrah, T, Li, H, Kuruc, J, Schmitz, J, McGee, K, Hicks, C, Eron, J |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
2012
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