Population-specific risk of type 2 diabetes conferred by HNF4A P2 promoter variants: a lesson for replication studies.

Population-specific risk of type 2 diabetes conferred by HNF4A P2 promoter variants: a lesson for replication studies.

OBJECTIVE: Single nucleotide polymorphisms (SNPs) in the P2 promoter region of HNF4A were originally shown to be associated with predisposition for type 2 diabetes in Finnish, Ashkenazi, and, more recently, Scandinavian populations, but they generated conflicting results in additional populations. W...

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Main Authors: Barroso, I, Luan, J, Wheeler, E, Whittaker, P, Wasson, J, Zeggini, E, Weedon, M, Hunt, S, Venkatesh, R, Frayling, T, Delgado, M, Neuman, R, Zhao, J, Sherva, R, Glaser, B, Walker, M, Hitman, G, McCarthy, M, Hattersley, A, Permutt, M, Wareham, N, Deloukas, P
פורמט: Journal article
שפה:English
יצא לאור: 2008

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