A plasmid-encoded peptide from Staphylococcus aureus induces anti-myeloperoxidase nephritogenic autoimmunity

A plasmid-encoded peptide from Staphylococcus aureus induces anti-myeloperoxidase nephritogenic autoimmunity

<p>Autoreactivity to myeloperoxidase (MPO) causes anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), with rapidly progressive glomerulonephritis. Here, we show that a&nbsp;<em>Staphylococcus aureus</em>&nbsp;peptide, homologous to an immunodominant MPO...

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Opis bibliograficzny
Główni autorzy: Ooi, JD, Jiang, J-H, Eggenhuizen, PJ, Chua, LL, van Timmeren, M, Loh, KL, O'Sullivan, KM, Gan, PY, Zhong, Y, Tsyganov, K, Shochet, LR, Ryan, J, Stegeman, CA, Fugger, L, Reid, HH, Rossjohn, J, Heeringa, P, Holdsworth, SR, Peleg, AY, Kitching, AR
Format: Journal article
Język:English
Wydane: Nature Research 2019

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