A plasmid-encoded peptide from Staphylococcus aureus induces anti-myeloperoxidase nephritogenic autoimmunity

<p>Autoreactivity to myeloperoxidase (MPO) causes anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), with rapidly progressive glomerulonephritis. Here, we show that a&nbsp;<em>Staphylococcus aureus</em>&nbsp;peptide, homologous to an immunodominant MPO...

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Bibliographic Details
Main Authors: Ooi, JD, Jiang, J-H, Eggenhuizen, PJ, Chua, LL, van Timmeren, M, Loh, KL, O'Sullivan, KM, Gan, PY, Zhong, Y, Tsyganov, K, Shochet, LR, Ryan, J, Stegeman, CA, Fugger, L, Reid, HH, Rossjohn, J, Heeringa, P, Holdsworth, SR, Peleg, AY, Kitching, AR
Format: Journal article
Language:English
Published: Nature Research 2019