A plasmid-encoded peptide from Staphylococcus aureus induces anti-myeloperoxidase nephritogenic autoimmunity

<p>Autoreactivity to myeloperoxidase (MPO) causes anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), with rapidly progressive glomerulonephritis. Here, we show that a&nbsp;<em>Staphylococcus aureus</em>&nbsp;peptide, homologous to an immunodominant MPO...

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প্রধান লেখক: Ooi, JD, Jiang, J-H, Eggenhuizen, PJ, Chua, LL, van Timmeren, M, Loh, KL, O'Sullivan, KM, Gan, PY, Zhong, Y, Tsyganov, K, Shochet, LR, Ryan, J, Stegeman, CA, Fugger, L, Reid, HH, Rossjohn, J, Heeringa, P, Holdsworth, SR, Peleg, AY, Kitching, AR
বিন্যাস: Journal article
ভাষা:English
প্রকাশিত: Nature Research 2019