A plasmid-encoded peptide from Staphylococcus aureus induces anti-myeloperoxidase nephritogenic autoimmunity

<p>Autoreactivity to myeloperoxidase (MPO) causes anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), with rapidly progressive glomerulonephritis. Here, we show that a&nbsp;<em>Staphylococcus aureus</em>&nbsp;peptide, homologous to an immunodominant MPO...

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Autors principals: Ooi, JD, Jiang, J-H, Eggenhuizen, PJ, Chua, LL, van Timmeren, M, Loh, KL, O'Sullivan, KM, Gan, PY, Zhong, Y, Tsyganov, K, Shochet, LR, Ryan, J, Stegeman, CA, Fugger, L, Reid, HH, Rossjohn, J, Heeringa, P, Holdsworth, SR, Peleg, AY, Kitching, AR
Format: Journal article
Idioma:English
Publicat: Nature Research 2019