A plasmid-encoded peptide from Staphylococcus aureus induces anti-myeloperoxidase nephritogenic autoimmunity

A plasmid-encoded peptide from Staphylococcus aureus induces anti-myeloperoxidase nephritogenic autoimmunity

<p>Autoreactivity to myeloperoxidase (MPO) causes anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), with rapidly progressive glomerulonephritis. Here, we show that a&nbsp;<em>Staphylococcus aureus</em>&nbsp;peptide, homologous to an immunodominant MPO...

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Hlavní autoři: Ooi, JD, Jiang, J-H, Eggenhuizen, PJ, Chua, LL, van Timmeren, M, Loh, KL, O'Sullivan, KM, Gan, PY, Zhong, Y, Tsyganov, K, Shochet, LR, Ryan, J, Stegeman, CA, Fugger, L, Reid, HH, Rossjohn, J, Heeringa, P, Holdsworth, SR, Peleg, AY, Kitching, AR
Médium: Journal article
Jazyk:English
Vydáno: Nature Research 2019

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