Kinetic resolution of quaternary and tertiary beta-hydroxy esters.

Selectivity factors: The resolution of tertiary and secondary alcohols, which arise from ketone and aldehyde aldol additions, proceeds in the presence of (1S, 2R)-N-methylephedrine (see example). The method is technically simple, easily scalable, and provides tertiary and secondary alcohols in high...

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Bibliographic Details
Main Authors: Schipper, D, Rousseaux, S, Fagnou, K
Format: Journal article
Language:English
Published: 2009