Kinetic resolution of quaternary and tertiary beta-hydroxy esters.
Selectivity factors: The resolution of tertiary and secondary alcohols, which arise from ketone and aldehyde aldol additions, proceeds in the presence of (1S, 2R)-N-methylephedrine (see example). The method is technically simple, easily scalable, and provides tertiary and secondary alcohols in high...
| Main Authors: | , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
2009
|
| Summary: | Selectivity factors: The resolution of tertiary and secondary alcohols, which arise from ketone and aldehyde aldol additions, proceeds in the presence of (1S, 2R)-N-methylephedrine (see example). The method is technically simple, easily scalable, and provides tertiary and secondary alcohols in high enantiomeric ratios. © 2009 Wiley-VCH Verlag GmbH and Co. KGaA. |
|---|