PTEN: tumour suppressor, multifunctional growth regulator and more.
The tumour suppressor gene PTEN is mutated in a wide range of human cancers at a frequency roughly comparable with p53. In addition, germline PTEN mutations are associated with several dominant growth disorders. The molecular and cellular basis of these disorders has been elucidated by detailed in v...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2003
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