The T-box transcription factor Eomesodermin governs haemogenic competence of yolk sac mesodermal progenitors
Extra-embryonic mesoderm (ExM)-composed of the earliest cells that traverse the primitive streak-gives rise to the endothelium as well as haematopoietic progenitors in the developing yolk sac. How a specific subset of ExM becomes committed to a haematopoietic fate remains unclear. Here we demonstrat...
Main Authors: | , , , , , , , , , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Springer Nature
2021
|