A single molecule assay to probe monovalent and multivalent bonds between hyaluronan and its key leukocyte receptor CD44 under force
Glycosaminoglycans (GAGs), a category of linear, anionic polysaccharides, are ubiquitous in the extracellular space, and important extrinsic regulators of cell function. Despite the recognized significance of mechanical stimuli in cellular communication, however, only few single molecule methods are...
Main Authors: | Bano, F, Banerji, S, Howarth, M, Jackson, D, Richter, R |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Nature Publishing Group
2016
|
Similar Items
-
Structure of the regulatory hyaluronan binding domain in the inflammatory leukocyte homing receptor CD44
by: Teriete, P, et al.
Published: (2004) -
Structure of the regulatory hyaluronan binding domain in the inflammatory leukocyte homing receptor CD44.
by: Teriete, P, et al.
Published: (2004) -
Interactions between CD44 and hyaluronan in leukocyte trafficking
by: Braedon eMcDonald, et al.
Published: (2015-02-01) -
Characterization of a functional hyaluronan-binding domain from the human CD44 molecule expressed in Escherichia coli.
by: Banerji, S, et al.
Published: (1998) -
Development of functionally relevant potency assays for monovalent and multivalent vaccines delivered by evolving technologies
by: Gautam Sanyal
Published: (2022-05-01)