Protein O-GlcNAcylation promotes trophoblast differentiation at implantation

Embryo implantation begins with blastocyst trophectoderm (TE) attachment to the endometrial epithelium, followed by the breaching of this barrier by TE-derived trophoblast. Dynamic protein modification with O-linked β-N-acetylglucosamine (O-GlcNAcylation) is mediated by O-GlcNAc transferase and O-Gl...

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Bibliographic Details
Main Authors: Ruane, PT, Tan, CMJ, Adlam, DJ, Kimber, SJ, Brison, DR, Aplin, JD, Westwood, M
Format: Journal article
Language:English
Published: MDPI 2020