Long noncoding RNAs CUPID1 and CUPID2 mediate breast cancer risk at 11q13 by modulating the response to DNA damage

Breast cancer risk is strongly associated with an intergenic region on 11q13. We have previously shown that the strongest risk-associated SNPs fall within a distal enhancer that regulates CCND1. Here, we report that, in addition to regulating CCND1, this enhancer regulates two estrogen-regulated lon...

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Detalles Bibliográficos
Main Authors: Betts, JA, Marjaneh, M, Al-Ejeh, F, Clark, MB
Formato: Journal article
Idioma:English
Publicado: Elsevier 2017