The mini-driver model of polygenic cancer evolution.
Much of cancer genetics research has focused on the identification of the most-important somatic mutations ('major drivers') that cause tumour growth. However, many mutations found in cancer might not be major drivers or 'passenger' mutations, but instead might have relatively we...
Main Authors: | , , |
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Format: | Journal article |
Language: | English |
Published: |
Nature Publishing Group
2015
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