A synthetic cyclitol-nucleoside conjugate polyphosphate is a highly potent second messenger mimic
Reactions that form sec–sec ethers are well known, but few lead to compounds with dense functionality around the O-linkage. Replacement of the α-glucopyranosyl unit of adenophostin A, a potent D-myo-inositol 1,4,5-trisphosphate (IP3R) agonist, with a D-chiro-inositol surrogate acting substantially a...
| Main Authors: | , , , |
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| Format: | Journal article |
| Published: |
Royal Society of Chemistry
2019
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