Targeting bromodomains: epigenetic readers of lysine acetylation.
Lysine acetylation is a key mechanism that regulates chromatin structure; aberrant acetylation levels have been linked to the development of several diseases. Acetyl-lysine modifications create docking sites for bromodomains, which are small interaction modules found on diverse proteins, some of whi...
Váldodahkkit: | , |
---|---|
Materiálatiipa: | Journal article |
Giella: | English |
Almmustuhtton: |
2014
|