Targeted sequencing from cerebrospinal fluid for rapid identification of drug-resistant tuberculous meningitis

Mortality from tuberculous meningitis (TBM) remains around 30%, with most deaths occurring within 2 months of starting treatment. Mortality from drug-resistant strains is higher still, making early detection of drug resistance (DR) essential. Targeted next-generation sequencing (tNGS) produces high...

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Bibliographic Details
Main Authors: Tram, TTB, Trieu, LPT, Nhat, LTH, Thu, DDA, Quang, NL, Bang, ND, Chau, TTH, Thwaites, GE, Walker, TM, Ha, VTN, Thuong, NTT
Format: Journal article
Language:English
Published: American Society for Microbiology 2024