Functional polymorphisms in the FCN2 gene are not associated with invasive pneumococcal disease.

L-ficolin is a pattern-recognition molecule which binds lipoteichoic acid and Gram-positive bacteria and activates the lectin pathway of complement. Five common functional polymorphisms have recently been identified in the FCN2 gene which encodes L-ficolin: three promoter polymorphisms (at positions...

Полное описание

Библиографические подробности
Главные авторы: Chapman, S, Vannberg, F, Khor, C, Segal, S, Moore, C, Knox, K, Day, N, Davies, R, Crook, D, Hill, A
Формат: Journal article
Язык:English
Опубликовано: 2007