The influence of antigenic variation on cytotoxic T lymphocyte responses in HIV-1 infection.

The propensity of HIV-1 for genetic variation, a consequence of error-prone reverse transcription combined with high rates of replication, is thought to contribute to the establishment of persistent infection in the host despite the presence of a vigorous antiviral immune response. Protective immuni...

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Bibliographic Details
Main Authors: Price, D, Meier, U, Klenerman, P, Purbhoo, M, Phillips, R, Sewell, A
Format: Journal article
Language:English
Published: 1998