The role of ATF4 in hypoxia-induced cell death in cancer
<p>Cancer cells survive the harsh oxygen and nutrient deprivation of the tumour microenvironment through the selection of apoptosis-resistant and glycolytic clones (Cairns et al., 2011; Graeber et al., 1996). In particular, the integrated stress response (ISR) has been shown to be pivotal in...
| Main Authors: | , |
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| Format: | Thesis |
| Language: | English |
| Published: |
2011
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| Subjects: |