Engineering and characterization of a fluorescent native-like HIV-1 envelope glycoprotein trimer

Generation of a stable, soluble mimic of the HIV-1 envelope glycoprotein (Env) trimer on the virion surface has been considered an important first step for developing a successful HIV-1 vaccine. Recently, a soluble native-like Env trimer (BG505 SOSIP.664) has been described. This protein has facilit...

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Bibliographic Details
Main Authors: Pritchard, L, Crispin, M, Sliepen, K, van Montfort, T, Ozorowski, G, Ward, A, Sanders, R
Format: Journal article
Published: MDPI 2015