Upregulation of eNOS and unchanged energy metabolism in increased susceptibility of the aging type 2 diabetic GK rat heart to ischemic injury.

We investigated the tolerance of the insulin-resistant diabetic heart to ischemic injury in the male Goto-Kakizaki (GK) rat, a model of type 2 diabetes. Changes in energy metabolism, nitric oxide (NO) pathway, and cardiac function were assessed in the presence of physiological substrates. Age-matche...

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Príomhchruthaitheoirí: Desrois, M, Clarke, K, Lan, C, Dalmasso, C, Cole, M, Portha, B, Cozzone, P, Bernard, M
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: 2010