ADGRL4/ELTD1 silencing in endothelial cells induces ACLY and SLC25A1 and alters the cellular metabolic profile

Adhesion G Protein-Coupled Receptor L4 (ADGRL4/ELTD1) is an endothelial cell adhesion G protein-coupled receptor (aGPCR) which regulates physiological and tumour angiogenesis, providing an attractive target for anti-cancer therapeutics. To date, ADGRL4/ELTD1′s full role and mechanism of function wit...

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Bibliographic Details
Main Authors: Favara, DM, Zois, CE, Haider, S, Pires, E, Sheldon, H, McCullagh, J, Banham, AH, Harris, AL
Format: Journal article
Language:English
Published: MDPI 2019