A well-conserved Plasmodium falciparum var gene shows an unusual stage-specific transcript pattern.
The var multicopy gene family encodes Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) variant antigens, which, through their ability to adhere to a variety of host receptors, are thought to be important virulence factors. The predominant expression of a single cytoadherent PfEMP1 type...
Autori principali: | Kyes, SA, Christodoulou, Z, Raza, A, Horrocks, P, Pinches, R, Rowe, J, Newbold, C |
---|---|
Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
2003
|
Documenti analoghi
Documenti analoghi
-
Transcription of subtelomerically located var gene variant in Plasmodium falciparum appears to require the truncation of an adjacent var gene.
di: Horrocks, P, et al.
Pubblicazione: (2004) -
Effect of var gene disruption on switching in Plasmodium falciparum.
di: Horrocks, P, et al.
Pubblicazione: (2002) -
Plasmodium falciparum var gene expression is developmentally controlled at the level of RNA polymerase II-mediated transcription initiation.
di: Kyes, S, et al.
Pubblicazione: (2007) -
A simple RNA analysis method shows var and rif multigene family expression patterns in Plasmodium falciparum.
di: Kyes, S, et al.
Pubblicazione: (2000) -
Stage-specific merozoite surface protein 2 antisense transcripts in Plasmodium falciparum.
di: Kyes, S, et al.
Pubblicazione: (2002)