Automated picking of amyloid fibrils from cryo-EM images for helical reconstruction with RELION

Cryogenic electron microscopy (cryo-EM) is an important tool for determining the molecular structure of proteins and protein assemblies, including helical assemblies such as amyloid fibrils. In reconstruction of amyloid fibril structures from cryo-EM images, an important early step is the selection...

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Bibliographic Details
Main Authors: Thurber, KR, Yin, Y, Tycko, R
Format: Journal article
Language:English
Published: Elsevier 2021