SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids

SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids

<p>Kidney failure is frequently observed during and after COVID-19, but it remains elusive whether this is a direct effect of the virus. Here, we report that SARS-CoV-2 directly infects kidney cells and is associated with increased tubule-interstitial kidney fibrosis in patient autopsy samples...

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Detaylı Bibliyografya
Asıl Yazarlar: Jansen, J, Reimer, KC, Nagai, JS, Varghese, FS, Overheul, GJ, de Beer, M, Roverts, R, Daviran, D, Fermin, LAS, Willemsen, B, Beukenboom, M, Djudjaj, S, von Stillfried, S, van Eijk, LE, Mastik, M, Bulthuis, M, Dunnen, WD, van Goor, H, Hillebrands, J-L, Triana, SH, Alexandrov, T, Timm, M-C, van den Berge, BT, van den Broek, M, Nlandu, Q, Heijnert, J, Bindels, EMJ, Hoogenboezem, RM, Mooren, F, Kuppe, C, Miesen, P, Grünberg, K, Ijzermans, T, Steenbergen, EJ, Czogalla, J, Schreuder, MF, Sommerdijk, N, Akiva, A, Boor, P, Puelles, VG, Floege, J, Huber, TB, van Rij, RP, Costa, IG, Schneider, RK, Smeets, B, Kramann, R
Diğer Yazarlar: COVID Moonshot consortium
Materyal Türü: Journal article
Dil:English
Baskı/Yayın Bilgisi: Cell Press 2021

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