SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids

SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids

<p>Kidney failure is frequently observed during and after COVID-19, but it remains elusive whether this is a direct effect of the virus. Here, we report that SARS-CoV-2 directly infects kidney cells and is associated with increased tubule-interstitial kidney fibrosis in patient autopsy samples...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Jansen, J, Reimer, KC, Nagai, JS, Varghese, FS, Overheul, GJ, de Beer, M, Roverts, R, Daviran, D, Fermin, LAS, Willemsen, B, Beukenboom, M, Djudjaj, S, von Stillfried, S, van Eijk, LE, Mastik, M, Bulthuis, M, Dunnen, WD, van Goor, H, Hillebrands, J-L, Triana, SH, Alexandrov, T, Timm, M-C, van den Berge, BT, van den Broek, M, Nlandu, Q, Heijnert, J, Bindels, EMJ, Hoogenboezem, RM, Mooren, F, Kuppe, C, Miesen, P, Grünberg, K, Ijzermans, T, Steenbergen, EJ, Czogalla, J, Schreuder, MF, Sommerdijk, N, Akiva, A, Boor, P, Puelles, VG, Floege, J, Huber, TB, van Rij, RP, Costa, IG, Schneider, RK, Smeets, B, Kramann, R
Awduron Eraill:	COVID Moonshot consortium
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	Cell Press 2021

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