BRAF/MAPK and GSK3 signalling converge to control MITF nuclear export

The close integration of the MAPK, PI3K, and WNT signaling pathways underpins much of development and is deregulated in cancer. In principle, combinatorial posttranslational modification of key lineage-specific transcription factors would be an effective means to integrate critical signaling events....

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Bibliographic Details
Main Authors: Goding, C, Ngeow, KC, Friedrichsen, HJ, Li, L, Zeng, Z, Andrews, S, Berridge, G, Picaud, S, Fischer, R, Lisle, R, Knapp, S, Filippakopoulos, P, Knowles, H, Steingrímsson, E, Borden, K, Patton, E
Format: Journal article
Published: National Academy of Sciences 2018