Evaluation of Aspergillus niger as host for virus-like particle production, using the hepatitis B surface antigen as a model.
The filamentous fungus Aspergillus niger was transformed with the hepatitis B virus S gene encoding the major viral envelope protein under control of the constitutive A. nidulans glyceraldehyde-3-phosphate dehydrogenase ( gpdA) promoter. Approximately seven copies of the expression cassette were int...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2003
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