The presence of tumor-infiltrating FOXP3+ lymphocytes correlates with intratumoral angiogenesis in endometrial cancer.

OBJECTIVES: CD4(+)CD25(+) regulatory T-cells (Tregs), that express the transcription factor FOXP3, suppress effector T-cell populations and can enable tumour cells to evade the host immune response. In this study, we investigated the numbers of FOXP3(+) Tregs in the normal and malignat endometrium...

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Autors principals: Giatromanolaki, A, Bates, G, Koukourakis, M, Sivridis, E, Gatter, K, Harris, A, Banham, A
Format: Journal article
Idioma:English
Publicat: 2008