Enantiospecific, biosynthetically inspired formal total synthesis of (+)-liphagal.
A biosynthetically inspired synthesis of (+)-liphagal has been achieved from (+)-sclareolide in 13 steps (9% overall yield). The key step is a biomimetic ring expansion of a highly stabilized benzylic carbocation, which generates the seven-membered ring and the benzofuran of the natural product in a...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2010
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