Mitochondrial biogenesis and increased uncoupling protein 1 in brown adipose tissue of mice fed a ketone ester diet.

We measured the effects of a diet in which D-β-hydroxybutyrate-(R)-1,3 butanediol monoester [ketone ester (KE)] replaced equicaloric amounts of carbohydrate on 8-wk-old male C57BL/6J mice. Diets contained equal amounts of fat, protein, and micronutrients. The KE group was fed ad libitum, whereas the...

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Bibliographic Details
Main Authors: Srivastava, S, Kashiwaya, Y, King, M, Baxa, U, Tam, J, Niu, G, Chen, X, Clarke, K, Veech, R
Format: Journal article
Language:English
Published: 2012