What repeat expansion disorders can teach us about the Central Dogma

Pathogenic repeat sequences underlie several human disorders, including amyotrophic lateral sclerosis, Huntington's disease, and myotonic dystrophy. Here, we speak to several researchers about how repeat sequences have been implicated in affecting all aspects of the Central Dogma of molecular b...

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Bibliographic Details
Main Authors: Wang, ET, Freudenreich, CH, Gromak, N, Jain, A, Todd, PK, Nagai, Y
Format: Journal article
Language:English
Published: Cell Press 2023